Knowledge · Benchmark profile
Generates novel protein sequences under family, topology, globularity, and structural-motif constraints.
Data verified 27 Jul 2026 · Methodology 1.7.0
Benchmark score on Anthropic Protein Design evaluation
Claude Opus 5 leads at 42.5%.
Visual analysis
Switch between model placement, score distribution and descriptive provider averages. Every view uses the same sourced leaderboard.
1 ranked models · higher is better · labels show rank and score
| Model | Rank | Provider | Score |
|---|---|---|---|
| Claude Opus 5 | #1 | Anthropic | 42.5% |
One best score per model · higher is better
| Rank | Model | Provider | License | Evidence use | Score |
|---|---|---|---|---|---|
| #1 | Claude Opus 5 claude-opus-5 | Anthropic | closed | Estimated reference | 42.5% |
About Anthropic Protein Design evaluation
Generates novel protein sequences under family, topology, globularity, and structural-motif constraints. Results stay tied to the exact model variant and evaluation system. Multiple systems for the same model use the best published score on this page; overall Lumina scoring uses the median of ranking-eligible rows.
Open benchmark source ↗FAQ
Generates novel protein sequences under family, topology, globularity, and structural-motif constraints.
Claude Opus 5 by Anthropic currently leads with 42.5%.
1 model in the LuminaBench cohort have a qualifying score on this benchmark.
No. This benchmark is display-only and does not enter the overall Lumina composite.
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